Spindle cell myoepithelial carcinoma of the oral cavity a. The main objective of endodontic treatment is the prevention andor the elimination of apical periodontitis. Only the cells lining the vascular spaces and the epithelioid cells stain for endothelial markers cd31 and cd34. A simple working type classification is proposed here for spindle cell neoplasms of the oral cavity table 1. The spindle cell neoplasms of the oral cavity ncbi. The high prevalence of ks in this series is likely reflective of demographics unique to the san francisco bay area. Spindle cell hemangioendothelioma of the oral cavity. Mycobacterial spindle cell pseudotumor of the appendix. A simple working type classification proposed for the spindle.
Find anatomy healthy teeth tooth dental implant stock images in hd and millions of other royaltyfree stock photos, illustrations and vectors in the shutterstock collection. In the histologic assessment of spindle cell lesions, the simplified approach is to evaluate the spindle cells and the. Spindle cell carcinoma spcc an aggressive squamous cell carcinoma, variant, frequently. Illustration of molar, periodontal, mouth 42619522. Bagwan a, tanuja shet a, prashant bavi a, anil dcruz b. The concept at that time was that these lesions only seemed to occur in the jaws, they were found in the first two decades of life, more frequently in females approximately 2. Recent treatment trends, however, combine less extensive radiotherapy fields with. Submit your manuscripts at hindawi publishing corporation volume 2014 oral oncology journal of dentistry. Diagnosing this is particularly problematic but important when encountered in a needle core biopsy, as treatments of different entities are different. Depending upon the ground substance, tumors can be. The workup of spindle cell lesions of the breast requires the judicious use of immunohistochemical stains to arrive at the correct diagnosis, especially on coreneedle biopsy.
The floor of the mouth is an uncommon site for scl, and very few cases. Presence of this tumor type in the tongue has rarely been reported. Spindle cell carcinoma is an unusual neoplasm commonly observed in the oral cavity 1 and the larynx. Spindle cell neoplasms can affect the oral cavity and it is often very difficult for the oral pathologists to differentiate it from other similar microscopic simulates. Spindle cell hemangioma is an uncommon benign vascular tumor of the oral cavity. Clinical examination revealed an erythematous nonhealing ulcerated lesion covering the left posterior mandibular ridge, measuring approximately 34 cm in size with extension into the vestibule and buccal mucosa. Atypical fibroxanthoma is a pleomorphic spindle cell tumor of the dermis and its been known to be a benign lesion clinically. The bidirectional relationship between oral health and systemic health cannot be over emphasized.
Spindle cell carcinoma arising in maxilla is much rarer occurrence in literature 7 with few cases reported since 1957 table 1. Causes spindle cells arise among actively dividing connective tissueepithelial cells causes genetic predisposition chromosomal. The tumors generally begin in layers of connective tissue such as that under the skin, between muscles, and surrounding organs, and will generally start as a small lump with inflammation that grows. Spindle cell carcinoma, spindle cell lesions, head and neck. Originally presented on february 09, 2015 in park city, utah. Introduction spindle cell lesions affecting oral mucosa are quite diverse in nature and their diagnosis is always a challenge.
Sarcomatoid carcinoma sc is an unusual and aggressive variant of squamous cell carcinoma, which frequently recurs and metastasizes. Additionally, latent pathogenic microorganisms can become highly colonized on obturator prostheses. Spindle cell lesions of the bladder and urinary tract request pdf. When combined with a more obvious overlying lesion such. Longitudinal section in the tooth tooth anatomy stock. Illustration about a vector illustration of a longitudinal section in the human tooth to show tooth anatomy. From mertimial iiorpitaz, new fork city for several years the authors have been interested in certain pe culiar tumors of the skin and mucous membranes which have been desig nated as spindle cell epidermoid carcinomas. A clinical diagnosis of squamous cell carcinoma was made and an incisional biopsy was done.
May 05, 2014 spindle cell neoplasms can affect the oral cavity and it is often very difficult for the oral pathologists to differentiate it from other similar microscopic simulates. To make it possible to remove the obturator without patient anxiety and ensure the opportunity for denture cleaning, we have advocated the application of a separate bedtime obturator that closes only the defect cavity. Truelove, dds, msd n david dean, dds n samuel maltby n matthew griffith. Immunohistochemistry has no useful role in the diagnosis. Spindle cell melanocytic lesions follow the full spectrum of potential biological outcomes, and.
This is achieved by instrumentation, disinfection, and obturation of the rootcanal system in three dimensions. Apr 11, 2017 dentsply sirona orthodontics announces the expansion of treatment indications for the mtm minor tooth movement clearaligner. Health care providers realized the oral cavity maybe a potential source of implementation or infection due to a variety of reasons. Spindle cell carcinoma of the oral cavity and oropharynx.
List periodontal tissues most likely injured by this penetrating wound. Spindle cell myoepithelial carcinomas need to be differentiated from other spindle cell lesions of the oral cavity like sarcomatoid squamous carcinoma, melanoma, nerve sheath sarcoma, etc. Spindle cell sarcoma is a type of connective tissue cancer in which the cells are spindle shaped when examined under a microscope. Spindle cell carcinoma is a rare biphasic tumor consisting of epithelial and mesenchymal components. The most common malignant spindle cell tumor was ks, but other malignancies were rare. Pdf on jan 31, 2015, ezulia t and others published spindle cell carcinoma of the oral cavity. Spindle cell lesions of the breast university of utah. Tooth root pulp is home to two types of prized stem cells. Giant cell lesions of the jaws were separated out from other jaw lesions by jaffe in 1953 when they were termed giant cell reparative granulomas. Guttapercha is the most widely used and accepted obturation material. Thirteen spindlecell tumors of the upper respiratory tract, oral cavity, and skin of face have. Spindle cell lesions are seen frequent enough that one ought to have a solid approach to em a general introduction to spindle cells is found in the spindle cell article. Although more common in other sites in the body, spindle cell neoplasms are rare in the oral cavity, as this study has shown.
While some are malignant, others are benign or simply reactive in. Factors affecting outcome hsinghao su1, sautung chu 1, yuyi hou1,2, kuoping chang, chiajung chen3 departments of 1otorhinolaryngology and 3pathology, kaohsiung veterans general hospital, and 2fooyin university hospital, kaohsiung, taiwan, r. Oral spindle cell lipoma oral medicine and pathology oral spindle cell lipoma. Mycobacterial spindle cell pseudotumor of the appendix vermiformis in a patient with aids carlos alberto basiliodeoliveira, alter a.
The risk for tooth extractions or other oral health complications as a result of cancer and cancer treatment varies depending upon the course of treatment and type of cancer. Herein, a case of 55yearold woman who presented with a polypoid lesion at her tongue has been reported. The movement of the teeth into their functional positions in the oral cavity. The wound enters the alveolar mucosa near the apex of a lower premolar tooth and extends from the surface mucosa all the way through the tissues to the premolar tooth root. Atraumatic extraction of a maxillary lateral incisor decayed. Many of these lesions will be amenable to surgical resection using transoral approaches including transoral robotic surgery tors. Immunohistochemical detection of hhv8 lna1 and d240 are useful tools to differentiate kaposi sarcoma from other vascular tumors. Corrigendum to tooth reattachment and palatal veneer on a. Vascular tumours with a prominent spindle cell component. Aug 09, 2017 spindle cell lesions of oral cavity part i 1. Narrow band light imaging of oral mucosa in routine dental patients. Mandible, mandibular cystic lesions, mandibular odontogenic solid tumors, toothrelated sclerotic mandibular lesions, nonodontogenic mandibular tumors the mandible is a physiologically complex bone that plays a role in phonation, mastication, and jaw stability.
The spindle cell component may be accompanied by scattered osteoclastic giant cells. This classification is based on the predominance of spindle cells in the histopathology of the lesions of the oral cavity. We report here a case of spindle cell carcinoma arising from the maxilla in a. There is no approved working classification for spindle cell neoplasms of the oral cavity in the literature. The entities, both benign and malignant, that compose the spindle cell lesions of the breast will be discussed. Professor of pathology and translation molecular pathology section chief of breast pathology 23rdannual seminar in pathology outline morphologic features of spindle cells lesions differential diagnosis case presentations wide spectrum bland, low grade spindle cells. The tongue is a highly manipulative, muscular structure, that contributes to chewing, swallowing, and sensing food. Sep 23, 2016 the majority of head and neck cancers arise from the oral cavity and oropharynx. Spindle cell carcinoma of the nasal cavity semantic scholar. In this case a maxillary lateral incisor decayed to gumline with fracture was extracted in preparation for an immediate dental implant using physics forceps. Assessment of value in detection of mucosal changes edmond l. A case report find, read and cite all the research you need on researchgate. Extension into structures, such as the tongue, cheek, oral cavity, alveolus or.
For some, chemo or radiation treatment can cause changes in the mouth. The clear aligner combines proven orthodontic techniques with advanced digital modeling to provide dental professionals with a streamlined solution for treating minor anterior misalignments. Histopathologically, the tumor is composed of interlacing bundles of spindle cells with wavy nuclei 3. Electron microscopy often shows the presence of junctional complexes between tumor cells, with or without pericellular basal lamina and cytoplasmic skeins of intermediate filaments. Pdf giant cells are large mononucleated or multinucleated cells that are seen in a.
The tongue often protrudes from the anterior opening of the oral cavity. Surgery was performed and pathologic examination revealed a spindle cell carcinoma. It is considered to be a biphasic tumor made up of cells from squamous and spindle cells carcinoma with a sarcomatous aspect, but of epithelial origin. Contents introduction causes for development of spindle cell tumors various classifications proposed for spindle cell lesions clinical and histological features of. Department of oral and maxillofacial surgery, kobe university graduate school of medicine. Spindle cell lesions of oral cavity part i slideshare. Jul 18, 2007 spindle cell lesions of the breast represent an interesting diagnostic problem, as the differential diagnoses are wide. The first, pluripotent stem cells, have the ability to become any cell in the organism from which theyre drawn.
Learn vocabulary, terms, and more with flashcards, games, and other study tools. The giant cell lesions of oral cavity have been classified on the basis of. Dental assisting exam 2 at central educational center studyblue. The diagnosis and management of giant cell lesions of the. International journal of contemporary medicine surgery and radiology. Spindle cell lesions of the urinary tract encompass a variety of benign and malignant tumours as well as a group of lesions of controversial.
A rare spindle cell neoplasm bernardoferreira brasileiro 1, pauloricardosaquete martinsfilho 1, martarabello piva, luizcarlosferreira da silva 1, cassianofranciscoweege nonaka 2, marciacristinada costa miguel 2 1 department of oral pathology, dentistry school, federal university of sergipe, sergipe. Improved transoral surgical tool design by ct measurements of. Spindle cell lipoma scl is a rare variety of lipoma that mostly arises in male patients and rarely affects the oral cavity. The diagnosis often represents a clinicalpathological. These cells may give rise to giantcell tumors of the alveolar ridge known as giant cell epnlides.
Seminar on spindle cell tumors of the oral cavity part i by. After completion of root canal therapy on a maxillary first premolar with moderate mesial and distal lesions and intact buccal and lingual surfaces, the conservative restoration of choice is aan mod amalgam mod composite resin mod gold onlay. To develop and control tors tools, precise dimensions of the oral cavity and pharynx are desirable. A patient involved in an automobile accident receives a penetrating wound involving the oral cavity. Thousands of new, highquality pictures added every day. Diagnosis and management of common oral and maxillofacial. When local oral disease is present it may have a direct impact on the systemic health of the individual. Pdf melanocytic lesions show great morphological diversity in their architecture and the. Spindle cell carcinoma of the breast japanese journal of clinical. Diagnosis and management of oral and maxillofacial lesions is of paramount.